Studies of ILC2 in human atopic dermatitis are limited, though similar to asthma and chronic rhinosinusitis, elevation of TSLP and IL-33 is present in human atopic dermatitis [70, 71] and one recent report demonstrated that ILC2 are increased in skin lesions of atopic dermatitis patients compared with controls [38]. This evidence concerns the gene IL33 and atopic eczema.