TFII-I interacted with genes encoding for the heme-regulated eIF2α kinase HRI (EIF2AK1), the Cockayne syndrome-B (CS-B or ERCC6), heterochromatin protein 1 beta (Hp1 beta, CBX1) and TF ATF3 (Supplementary Figure S3). This evidence concerns the gene ERCC6 and Cockayne syndrome.