TCF4 and diffuse large B-cell lymphoma: A particularly intriguing possibility is suggested by the preferential expression of TCF4 (also known as E2–2) in the SPIBhigh/BATFlow-ABC-DLBCL subgroup, and the presence of several SPIB binding peaks across the TCF4 (E2–2) locus in OCI-LY3 and LY10 cells.