SPIB and diffuse large B-cell lymphoma: We examined the MYD88 mutation status of ABC-DLBCL cases in our cohort (62), and found a statistically significant association between cases with high SPIB and low BATF expression and the presence of a MYD88 mutation in general (7/9 cases, p-value = 0.015), or the common MYD88-L265P mutation in particular (6/9 cases, p-value = 0.03) (Figure 9C and Supplementary Table S8).