CLOCK and cancer: To investigate how the identified set of discriminative genes links cancer genes and circadian regulators we again used the text mining software GeneView to create interaction networks between i) the core-clock genes (Figure 2B) and the 45 discriminative genes (Table 2, Text S1); ii) a set of known colon cancer-related genes ([51], Table 3) and the 45 discriminative genes and iii) between all three sets of genes.