Studies by Zhou et al. [108] have shown that there is a significant increase in Tregs and FoxP3 expression and a decrease in Th17 cells, ROR ct and IL-17 expression in peripheral blood of NSCLC patients while compared to that in healthy patients, and Foxp3 levels correlated with levels of RORc and IL-17. The gene discussed is IL17A; the disease is non-small cell lung carcinoma.