INS and metabolic syndrome: Therefore, in our study, the presence of these phytoconstituents justified the fact that AqE-TFG effectively inhibit fat accumulation and ameliorate dyslipidemia in HFD-obese rats, which is due to prevention of impaired lipid digestion and absorption, in addition to improvement in glucose and lipid metabolism, enhancement of insulin sensitivity, increased antioxidant defense, and downregulation of lipogenic enzymes.