Interestingly, PEBP1 expression levels are decreased in primary tumors (MSK/EMC dataset) that relapse to brain and lungs, thereby confirming the accuracy of our analysis, while RARRES3 levels in these clinical samples have prognostic value exclusively for the prediction of lung metastasis (Supplementary Table S1). This evidence concerns the gene PLAAT4 and extraskeletal myxoid chondrosarcoma.