Finally, the differential pattern of basal expression among p53 targets is also observed in an analysis of 256 breast tumors for which p53 status was determined, where CDKN1A, DDB2 and GDF15 (but not GJB5) show higher expression in the p53 WT tumors (Figure 3—figure supplement 2C). This evidence concerns the gene GJB5 and breast neoplasm.