Among Hsa-miR-139-5p possible targets we found H2AFV, an histone family member, and Lysosome Transmembrane Protein 4-Beta (LAPTM4B), an oncoprotein originally identified in hepatocellular carcinomas [160]–[161], whose over-expression has been already associated with BC susceptibility and prognosis [162]–[163]. This evidence concerns the gene H2AZ2 and breast cancer.