Hsa-miR-320d, already found down-regulated in colon cancer cells [153], and Hsa-miR-139-5p, regulate genes involved in proliferation control (antizyme inhibitor 1, AZIN1; forkhead box M1, FOXM1; RAD51 associated protein 1, RAD51AP1) [154]–[156], and transcription regulation (DNA replication and sister chromatid cohesion 1, DSCC1; RAD21 yeast homologue, RAD21) key processes for G3 development. The gene discussed is RAD21; the disease is malignant colon neoplasm.