ADIPOQ and type 2 diabetes mellitus: Over the years, linkage studies have reported many predisposing associations with chromosomal regions for T2D, including segments in chromosomes 5 and 10, and have identified putative, causative genetic variants in CAPN10 [41], ENPP1 [42], HNF4A [43, 44], and ACDC (also called ADIPOQ) [45], but most of the findings from these reports could not be replicated.