When we subclassified that cohort into NL, SS, and NASH, we observed that CB1 mRNA expression was significantly higher in NASH compared with SS (SS: 0.09 ± 0.07; NASH: 0.14 ± 0.03; P < 0.010) (Figure 1(a)). Here, CNR1 is linked to metabolic dysfunction-associated steatohepatitis.