We also demonstrated that SBL has synergistic effects with the TNF-related apoptosis-inducing ligand (TRAIL) [46, 47]. R. catesbeiana RNase (RC-RNase), purified from R. catesbeiana oocytes by Liao et al. in 1992, is identical to SBL [48, 49] and also has cancer-selective antitumor activity and synergistic effects with interferon-γ (IFN-γ) [50, 51]. The gene discussed is TNFSF10; the disease is cancer.