Paterson and colleagues studied this phenotype further and discovered that IFN-γ stimulation of TC.1 tumor cells results in the production of a chemokine, CXCL9, that mediates infiltration of CD8+ T cells into TC.1 tumors after Lm-LLO-E7 vaccination (Guirnalda et al., 2013). The gene discussed is CD8A; the disease is neoplasm.