Due to the high degree of homology between human and rodent Her2/neu and the presence of defined H-2q epitopes within the portions from human Her2 (Seavey et al., 2009b), mouse breast tumor models such as NT-2, 4T1, and the MMTV-Her2/neu transgenic could be used to assess efficacy. Here, ERBB2 is linked to breast neoplasm.