UFM1 and infection: Vaccination with null mutants of the biopterin transporter 1 (Bt1) gene, involved in biopterin transport; centrin (Cen), involved in the cell division cycle; p27, a cytochrome c oxidase complex component; Lpg-2 (Golgi GDP mannose transporter), involved in phosphoglycan synthesis, which is essential for host–parasite interactions or ubiquitin fold modifier-1 (Ufm-1) gene involved in fatty acid metabolism produced a strong protective immunity against challenge infection.