The main and new findings of the present study are that exercise training in an ischemic model of CHF: 1) Normalizes AngII concentration in soleus and plantaris muscle; 2) Decreases AT1 receptors towards normal levels in soleus muscle; 3) Increases Ang-(1–7)/AngII ratio in plasma and soleus; and 4) Increases Mas receptor mRNA expression in soleus muscle. The gene discussed is AGT; the disease is congestive heart failure.