Expression of the proteins was consistent with the proteomic discovery study results, as HDL-associated-SAA was significantly increased in CHD individuals compared with controls (126.5±67.3 μg/mg of HDL vs. 68.7±12.4 μg/mg of HDL, n = 10/group, P = 0.024) (Figure 3A), and HDL-associated-apoC-I was significantly reduced in the CHD patients relative to the controls (68.8±14.4 μg/mg of HDL vs. 81.1±10.6 μg/mg of HDL, P = 0.040) (Figure 3B). Here, SAA2 is linked to coronary artery disorder.