TLN1 and neoplasm: Talin-1 demonstrated the highest fold-change in tumor tissues (Table A in File S1, Fisher's exact test, p<0.05) and its expression was validated by immunoblotting (Figure 3a, Student's t-test, p<0.05), qRT-PCR (Figure 3b, Student's t-test, p<0.05) and immunohistochemistry in OSCC human tissues (Figure 4, Students' t-test, p<0.0001).