In patients with acute coronary syndromes who have undergone percutaneous intervention, nearly half of the individuals having major adverse cardiovascular events were found to carry a genotype associated with increased risk alleles of ABCB1 and CYP2C19 [5], suggesting that the improved prediction of cardiovascular events could be possible when combined with both ABCB1 and CYP2C19 genotypes than the application of individual gene alone. This evidence concerns the gene ABCB1 and acute coronary syndrome.