FADS1 and coronary artery disorder: Three members of the fatty acid desaturase (FADS) gene family on chromosome 11q12–13 [95,96] include FADS1 and FADS2, demonstrated to code for the enzymes, Δ5 and Δ6 desaturase activities, respectively, while less is known about FADS3. Over the past decade, genome-wide association studies (GWAS) have identified a number of genetic polymorphisms that convey increased risk for coronary artery disease, diabetes, cancer, and other common diseases.