TUG1 and osteosarcoma: However, TUG1 is overexpressed in bladder cancer, gastric cancer and osteosarcoma.32, 33, 34 This finding is probably because lncRNAs exhibit remarkably tissue-specific expression patterns than protein-coding genes.6, 35 These results indicate that TUG1 may have a tissue-specific expression pattern and exhibit important role in NSCLC development and progression.