All of the tumors showed positive immunostaining of HOXB7 protein, both in lung squamous cell carcinoma and lung adenocarcinoma tissues: 12 of 50 NSCLC cases (24.0%) showed weakly positive staining and 38 NSCLC cases (76%) showed strongly positive staining. The gene discussed is HOXB7; the disease is non-small cell lung carcinoma.