CXCL8 and ornithine translocase deficiency: Hypo-HHH was characterized by an increased rate of migrated macrophages in the bone marrow, severe leukocytopenia, and high serum IL-8 levels; however, there was no increase in the absolute number of macrophages, indicating that the functional activation of macrophages resulted in the engulfment of bone marrow hematopoietic cells.