Other factors associated with increased risk include 15 % or more of bone marrow macrophages (odds ratio = 9.42; 95 % CI, 2.14–41.58, p < 0.01), sepsis (odds ratio = 7.77; 95 % CI, 1.48–40.9, p < 0.05), and high serum IL-6 levels (odds ratio = 1.00; 95 % CI, 1.00–1.0001, p < 0.05). The gene discussed is IL6; the disease is Sepsis.