Significantly higher mRNA expression of GPx1, CAT, and Cu-Zn SOD was observed in the fetal liver of the HF group, while the mRNA expression of Trx2, HIF-1a, and JNK1 was lower in the fetal liver of the HF group compared to the SB group (P<0.05). The gene discussed is MAPK8; the disease is hydrops fetalis.