MST1 and Autoimmunity: Of note, sublethally irradiated WT animals reconstituted with syngeneic Mst1−/− bone marrow cells exhibit substantially lower disease severity and incidence compared to animals reconstituted with WT bone marrow (K. Salojin, unpublished observation), providing further evidence for an important role of the lymphoid compartment in the resistance of Mst1−/− mice to autoimmunity.