To understand the impact of Scrib loss on the progression of mammary tumourigenesis, we compared the histopathological grading of tumours from MMTV-Cre;Scrib+/+ and MMTV-Cre;Scribflox/− mice at endpoint (1200 mm3 tumour volume) using a broadly accepted nomenclature and morphologic classification system [66]. This evidence concerns the gene SCRIB and neoplasm.