Pearson correlation coefficients were organized using a clustering algorithm to reveal highly positively co-regulated sets of probesets (Figure 2) whereby 4 probesets for SYK, 3 probesets for STAT3, 2 probesets for TNFAIP8, 2 probesets for GCLC and 1 probeset for DAD1 formed a metacluster of highly correlated expression values across 1063 leukemia samples. Here, SYK is linked to leukemia.