Acute coronary syndromes are among the rare adverse effects of HCV infection therapy32 that are probably attributed to IFN-induced vasospasms.33 The most notorious side effect of Ribavirin is hemolysis; the stress of a sudden onset of anemia due to hemolysis can induce myocardial infarction in persons with pre-existing coronary artery disease or stroke in those with cerebrovascular disease. Here, IFNA1 is linked to hemolysis.