SERPINA1 and acute kidney injury: If so, then its purported “pro-survival” activities might have relevance to AKI in at least two important respects: first, if AKI were to acutely induce AAT, it could potentially mitigate evolving renal damage; and second, if injury- induced renal AAT elevations were persistent in nature, it could potentially contribute to so called “ischemic pre-conditioning” or the “cytoresistant” state.