Another gene associated with thyroid function that was highlighted in our selection scans as top 10 ranking PBS signal in two south Siberian populations is THADA (Tables S6 and S12 in File S2) which is one of the few genes that has been confirmed to be significantly associated with Type 2 Diabetes in multiple studies; in European, Asian, and Native American cohorts [63], [64]. Here, THADA is linked to type 2 diabetes mellitus.