AD-PCR-Array data revealed that expression of genes directly involved in Aβ production such as App, Bace1, Psen1, Ncstn and Aph1a but not Adam9 were significantly increased in MS9II cells compared to MS cells (Figs. 1A; 2D; 3A, B, E and F). This evidence concerns the gene ADAM9 and Alzheimer disease.