To confirm the involvement of the MAPK signaling pathways in the lasiodin-mediated proliferation inhibion of NPC cells, we analyzed the effects of the ERK-selective inhibitor (U0126, 20 μM), JNK inhibitor (SB203580, 600 nM) and p38 inhibitor (SP600125, 2.5 μM) on the lasiodin-mediated proliferation inhibition by the MTT assays. This evidence concerns the gene MAPK8 and nasopharyngeal carcinoma.