Genetic mutation and gene polymorphism studies show that abnormalities in NBCn1 are pathologically associated with visual and hearing defects (Bok et al. 2003), vascular muscle contractility and hypertension (Boedtkjer et al. 2011), and breast cancer (Boedtkjer et al. 2012; Lauritzen et al. 2012). Here, SLC4A7 is linked to breast carcinoma.