This is in contrast to the reported ability of TSLP to shrink tumours in Notch-deficient skin (Demehri et al., 2012), but in agreement with the potent tumorigenic effect of TSLP in breast and pancreatic cancers (De Monte et al., 2011; Pedroza-Gonzalez et al., 2011). The gene discussed is TSLP; the disease is familial pancreatic carcinoma.