SRSF3 has also been proposed to be a proto-oncogene critical for cell proliferation and tumor induction and maintenance (Jia et al., 2010), whereas SRSF6 (SRp55) is amplified and is an oncoprotein in lung and colon cancers (Cohen-Eliav et al., 2013). Here, SRSF6 is linked to malignant colon neoplasm.