9 of the 55 proteins have previously been described altered in proteomic studies of glioma (APOA1, GFAP, HSPA5, PDIA3, GSTP1, UCHL1, HSPB1, HSPD1 and PRDX1; 8 of these 9 proteins were also altered in young GBM). The gene discussed is HSPA5; the disease is glioma.