19 of the 55 proteins have been reported to be putatively localised to mitochondria (OXCT1, ATP6V1E1, NAPG, NDUFS3, ACOT7, CKB, CKMT1A, DPYSL2, GLUL, HSPD1, IDH3A, PRDX1, PRDX3, PRDX5, PEBP1, SUCLA2, SOD1, UQCRFSL1 and VDAC2; 13 of these 19 proteins were also altered in young GBM). The gene discussed is SOD1; the disease is glioblastoma.