BRD2 and parasitic infectious disease: Aside from lower limits of detection (LoD) that afford earlier diagnoses, quantitative NAT data provide day-by-day measures of the rise and fall of parasitemia and allow for model-based assessments of liver-to-blood inocula levels and parasite multiplication rates, which can be used to calculate efficacy estimates for partially-effective liver vaccines and for blood-stage vaccines [42], [43].