Abnormal expression of genes related to apoptosis was also reported in bone marrow CD34+ cells isolated from three DBA patients with mutations in RPS19 and in remission from the disease (Gazda et al., 2006), and in a previous study by our group focused on unraveling the gene expression alterations in fibroblasts isolated from DBA patients with RPS19 mutations (Avondo et al., 2009). Here, CD34 is linked to Diamond-Blackfan anemia.