Recently, increased expression of SATB1 has been found to be associated with invasion and metastasis of various types of cancers, such as breast cancer, gastric cancer, rectal cancer, liver cancer and prostate cancer, indicating the significance of SATB1 as an independent prognostic factor as well as a potential therapeutic target in human malignancies [12], [17]–[21]. Here, SATB1 is linked to Familial prostate cancer.