MMP8 and Sepsis: Sepsis was independently associated with the following variables at the first day of ICU admission: higher MMP-8 concentrations (OR [95%CI] 1.107 [1.058–1.158], p < 0.0001), fibrinogen levels (1.010 [1.005–1.015, p = 0.0001), neutrophils counts (1.116 [1.014–1.228], p = 0.02), and number of organ failures (2.174 [1.117–4.229], p = 0.02), and lower concentrations of MMP-9 (0.995 [0.992–0.998], p = 0.0001).