CYP21A2 and adrenal cortex carcinoma: Upregulated: High expression of genes that encode growth factors: (IGF2 and TGFβ2), growth factor receptors: FGFR1, FGFR4,MST1R, TGFBR1, KCNQ1OT1 and GAPDH in ACC compared to ACADownregulated: Low expression of steroidogenesis genes: steroidogenic acute regulatory protein (StAR), CYP11A, HSD3B1, CYP11B1, CYP21A2 and CYP17 in ACA compared to ACC