CXCL8 and melanoma: Three genes among the differentially methylated panel were chosen to measure mRNA expression levels by qPCR (FGFR3, MCAM and IL8) according to the following selection criteria: we exclusively focused on genes that had not been previously referred to as methylated in melanomas; furthermore, FGFR3 was chosen in the context of histologic subtype and MCAM of Breslow thickness, while IL8, being a commonly methylated gene among distinct clinical groups was measured across in all categories (Breslow thickness, histologic subtype, ulceration and metastatic capacity).