ZNF253 and gingival fibromatosis-hypertrichosis syndrome: To determine whether these candidate genes are expressed in the skin and hair follicle, RT-PCR analysis was performed on RNA isolated from whole skin, which revealed that the ABCA5 and DGKZ genes are abundantly expressed, suggesting a potential role for these two genes in the pathogenesis of the CGHT phenotype, whereas ZNF253 is expressed at lower levels.