Interestingly, both CXCL-13 and CXCR5−/− mice are equally susceptible to infection with either Mtb H37Rv [20], [23] or Mtb HN878 described here, implicating IL-17-independent pathways in CXCL-13 induction during Mtb H37Rv infection. This evidence concerns the gene CXCL13 and infection.