A recent study identified annexin A11 as a novelnon-HLA susceptibility locus for sarcoidosis.(6) Many other loci encoding TNF-α and co-stimulatory molecules onantigen-presenting cells such as CD80 and CD86, as well as the chemokine receptors CCR2and CCR5, have been found to increase susceptibility to sarcoidosis.(7). This evidence concerns the gene ANXA11 and sarcoidosis.