Since first identification in 1995, mutations in MYO7A gene have been reported to be implicated in causing a wide phenotypic spectrum, including USH type 1 [8], an atypical form of USH mimicking USH type 3 [34], two types of nonsyndromic deafness: autosomal dominant nonsyndromic deafness-11 (DFNA11) [48] and autosomal recessive nonsyndromic deafness-2 (DFNB2) [49], [50], and even Leber congenital amaurosis [51]. The gene discussed is MYO7A; the disease is autosomal dominant nonsyndromic hearing loss 11.