In view of the evidence accounting for a cross-recognition of MAP3865c/ZnT8 homologues sequences in T1D subject [9], [10], [12] and due to the recently proposed theory which pictures MAP as one of the HT environmental trigger, acting trough a molecular mimicry mechanism [4], [5], we decided to investigate the sero-prevalence of anti-MAP/ZnT8 Abs among Sardinian HT patients. Here, DDX41 is linked to hematocrit.