For example, inflammatory-related genes and their respective proteins such as NFKB1[48], CCR1[49], SOCS3, JAK3[50], JUNB[51], RHOG[52], TIMP1[53], IL1beta[54]–[57], ITGAM [58], CD44 [59], [60], TLR5 [61]–[63] and CXCR1 [64], [65] from our Reactome analysis are known to be up-regulated in reproductive tissues and other biologic fluids during term labor or PTL with or without infection. This evidence concerns the gene IL1B and infection.