FGF2 and hypertrophy: In addition, administration of rat Hi-FGF-2, but not Lo-FGF-2 after myocardial infarction promoted cardiomyocyte and cardiac hypertrophy; in the same model, rat Lo-FGF-2, but not Hi-FGF-2, was capable of sustained cardioprotection and angiogenesis after myocardiac infarction[17].