Most gene products were upregulated in most cancers except for CDKN1A and OBFC2A. Importantly, for six of the eight genes, data were available for bladder cancer; all six (CDKN1A, CCND1, MDM2, TIMP3, MYC, and THBD) were strongly upregulated in that tumor. The gene discussed is TIMP3; the disease is neoplasm.