Although GOLPH3 was ubiquitously expressed in all tested tissues (human MTC panels I and II), it exhibited the highest transcript level in the placenta (average expression relative to reference HPRT, 2.99 ± 0.06 SEM), followed by prostate, ovary, and leucocytes (relative expression 1.50 ± 0.05, 1.13 ± 0.02, and 1.12 ± 0.04; respectively) (Fig.3E). This evidence concerns the gene GOLPH3 and medullary thyroid gland carcinoma.