To investigate this apparent discrepancy, we sought to conduct a meta-analysis to estimate the prognostic importance of tumor-infiltrating FoxP3+ T cells level for overall survival (OS) and disease-free survival (DFS) among patients with HCC, CRC and GC, aiming to gain insights into whether FoxP3+ T cells could provide useful guidance in the biological understanding and treatment of solid tumors. The gene discussed is FOXP3; the disease is colorectal carcinoma.